Following an agreement signed in 2019 between DLR and ONERA, AI4Aerospace workshops, on the use of Artificial Intelligence (AI) in aerospace, are organized every year. From May 19 to 21, the 5th AI4Aerospace workshop enabled the two organizations to exchange views on their most recent results. These focused on machine learning for physics and partial differential equations, AI methods for design and operations management, certification of AI-based solutions, and AI for signal and image processing, as well as for control and monitoring.